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| Research Interests |
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1. |
Genomic regulations of non-coding RNAs in spermatogonial stem cells |
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2. |
Developmental and genome biology |
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3. |
Nanotoxicology and nanomedicine |
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4. |
Semantic bioinformatics |
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5. |
Systems biology modeling and algorithm development |
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| Publications |
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1. |
Lee TL, Xiao A, Rennert OM. (2012) Identification of novel long noncoding RNA transcripts in male germ cells. Methods Mol Biol 825:105-14 |
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2. |
Lee TL, Raitano JM, Rennert OM, Chan SW, Chan WY. (2012) Accessing the genomic effects of naked nanoceria in murine neuronal cells. Nanomedicine 8(5):599-608 |
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3. |
Lee TL, Raygada MJ, Rennert OM. (2012) Integrative gene network analysis provides novel regulatory relationships, genetic contributions and susceptible target in autism spectrum disorders. Gene Apr 1; 496(2)88-96 |
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4. |
Kokkinaki M, Lee TL, He Z, Jiang J, Golestaneh N, Hofmann MC, Chan WY, Dym M. (2010) Age affects gene expression in mouse spermatogonial stem/progenitor cells. Reproduction 139(6):1011-20 |
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5. |
Cheung HH*, Lee TL*, Davis AJ, Taft DH, Rennert OM, Chan WY. (2010) Genome-wide DNA methylation profiling reveals novel epigenetically regulated genes and non-coding RNAs in human testicular cancer. Br J Cancer 19;102(2):419-27. |
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6. |
Lee TL, Li Y, Cheung HH, Claus J, Singh S, Sastry C, Rennert OM, Lau YF, Chan WY. (2010) GonadSAGE: a comprehensive SAGE database for transcript discovery on male embryonic gonad development. Bioinformatics 26(4):585-6. |
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7. |
Lee TL, Cheung HH, Claus J, Sastry C, Singh S, Vu L, Rennert O, Chan WY. (2009) GermSAGE. An Integrated Germ Cell Transcriptome Resource. Nucleic Acid Research D891-7. |
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8. |
Lee TL. (2008) Big Data: Open-source Format Needed to Aid Wiki Collaboration. (Sept 25) Nature Sept 25;455(7212):461. |
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9. |
Lee TL, Cheung HH, Rennert OM, Chan WY. (2008) The Paradox of DNA Methylation in Transcriptional Regulation. PLoS Biology Mar; 6(3). |
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10. |
Loercher A*, Lee TL*, Ricker JL, Howard A, Geoghegen J, Chen Z, Sunwoo JB, Sitcheran R, Chuang EY, Mitchell JB, Baldwin AS Jr, Van Waes C. (2004) Nuclear Factor-KB is an Important Modulator of the Altered Gene Expression Profile and Malignant Phenotype in Squamous Cell Carcinoma. Cancer Research 64(18):6511-23. |
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