Prof LI Gang 李剛
MBBS, D.Phil. (Oxon)
Rm 107A, Lo Kwee-Seong Integrated Biomedical Sciences Building, Area 39, CUHK, Shatin, NT, Hong Kong / Room 904, 9/F, Li Ka Shing Institute of Health Institute, CUHK, PWH Hospital
  (852) 39435745 (SBS Office) / (852) 37636153 (PWH Office)
 gangli@cuhk.edu.hk
 
 
   
   
 
 Research Interests
 
1. 
Controls of stem cell differentiation
   
2. 
Musculoskeletal tissue regeneration and tissue engineering
   
3. 
Mesenchymal stem cells systemic recruitment and homing mechanisms
   
4. 
The use of mesenchymal stem cells for gene therapy
   
5. 
Stem cell clinical applications and translational research
   
 
 Publications
 
1.
Zhang XB, Meng XM, Baylink D, Neises A, Kiroyan J, Su RJ, Kimberly P, Gridley D, Wang J, William KH, Lee W, Li G. (2013) Rapid and efficient reprogramming of human fetal and adult blood CD34+ cells into mesenchymal stem cells with a single factor. Cell Research, 1-15.
   
2.
Ni M, Rui YF, Tan Q, Liu Y, Xu LL, Chan KM, Wang Y, Li G. (2013) Engineered scaffold-free tendon tissue produced by tendon-derived stem cells. Biomaterials, 34: 2024-2037.
   
3.
Fan QM, Yue B, Bian ZY, Xu WT, Tu B, Dai KR, Li G, Tang TT. (2012) The CREB-Smad6-Runx2 axis contributes to the impaired osteogenesis potential of bone marrow stromal cells in fibrous dysplasia of bone. Journal of Pathology, 228(1):45-55
   
4.
Xu LL, Song C, Ni M, Meng, FB, Xie HQ, Li G. (2012) Cellular retinol-binding protein 1 (CRBP-1) regulates osteogenenesis and adipogenesis of mesenchymal stem cells through inhibiting RXR-a-induced B-catenin degradation. The International Journal of Biochemistry & Cell Biology, 44:612-619.
   
5.
Ni M, Cheng TY, Rui YF, Chan KM, Kuhstoss S, Ma YF, Sato M, Wang, Y, Li G. (2012) Dose-dependent enhancement of spinal fusion in rats with Teriparatide [PTH(1-34)]. Spine, 37(15):1275-1282.
   
6.
Zhang G, Guo B, Wu H, Tang T, Zhang B, Zheng L, He Y, Yang Z, Pan X, Chow H, To K, Li Y, Li D, Wang X, Wang Y, Lee K, Hou Z, Dong N, Li G, Leung K, Hung L, He F, Zhang L, Qin L. (2012) A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy. Nature Medicine, 18(2): 307-14
   
7.
Tang JQ, Luo ZH, Zhou GQ, Song C,Yu FL, Xiang JJ, Li G. (2011) Cis-regulatory functions of overlapping HIF-1alpha/E-box/AP-1-like sequences of CD164. BMC Molecular Biology, 12:44.
   
8.
Song C, Xiang J, Tang JQ, Hirst D, Zhou JW, Chan KM, Li G. (2011) Thymidine kinase gene modified bone marrow mesenchymal stem cells as vehicles for anti-tumor therapy.  Human Gene Therapy, 22(4):439-49.
   
9.
Song C, Li G. (2011) CXCR4 and MMP-2 are involved in mesenchymal stem cells homing and engraftment to the tumors.  Cytotherapy, 13(5): 549-61.
   
10.
Chen X, McClurg A, Zhou GQ, McCaiguea M, Armstrong MA, Li G. Chondrogenic-differentiation rectifies the immunosuppressive property of bone marrow-derived MSCs and the effect is partially due to the up-regulated expression of B7 molecules.  Stem Cells, 25:364-370.
   
   
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